Marvel Chronology Project

In IH2 380, Crazy Eight is sentenced to die for having killed Senator Ray Hartwell. He doesn't actually appear, being dead, but his widow, Mrs Beth Hartwell, does. Although the senator doesn't actually appear on-panel anywhere, he did exist in the Marvel Universe prior to being murdered.

INCOMING! 1 has Geoffrey Patrick, a charming senator from Indiana who wants to outlaw teenage superheroes.

It doesn't appear that Clive_Reston is maintaining this list anymore, but there's a Senator Irksome in NFAOS 5.